Treatment of Neurodevelopmental Disorders by Randi Jenssen Hagerman,Robert L. Hendren

Treatment of Neurodevelopmental Disorders
  • Title : Treatment of Neurodevelopmental Disorders
  • Author : Randi Jenssen Hagerman,Robert L. Hendren
  • Publisher : Oxford University Press (UK)
  • ISBN Code : 019993780X
  • Pages : 376
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

This cutting-edge book brings advances in genetics, neurobiology, and psychopharmacology to the clinic to enhance treatment for neurodevelopmental disorders. Significant progress has been made in identifying the neurobiological mechanisms of several disorders and targeted treatments are modifying the outcome of these disorders. However, the ability to utilize this knowledge has not been summarized in one place for the practicing clinician. This book will fill that gap by providing the theoretical underpinnings and the latest advances in targeted treatments. Several neurodevelopmental disorders are reviewed in detail including clinical features and behavioral phenotypes, standard treatments and new targeted treatments based on the latest advances in neurobiology and the animal model studies that have led to new treatments. The disorders covered include psychiatric disorders: schizophrenia, depression, autism and ADHD; single gene disorders including Tuberous Sclerosis, Fragile X Syndrome and fragile X- associated disorders, Angelman Syndrome, PKU, and Muscular Dystrophies; and complex genetic disorders such as Down syndrome. This book also highlights the commonalities across disorders and new genetic and molecular concepts in an easy to read format. This is a very exciting time for new targeted treatments and this volume is a landmark treatise on this new age of treatment.


Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders by Gupta, Sanjeev Kumar,Venkatesan, Srinivasan,Goswami, S.P.,Kumar, Rajeev

Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders
  • Title : Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders
  • Author : Gupta, Sanjeev Kumar,Venkatesan, Srinivasan,Goswami, S.P.,Kumar, Rajeev
  • Publisher : IGI Global
  • ISBN Code : 1522570055
  • Pages : 394
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Neurodevelopmental disorders encompass a group of conditions that can typically manifest during early childhood. These include intellectual disabilities, communication disorders, autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), specific learning disorder (SLD), and motor disorders. Early identification and assessment can be a valuable tool in determining diagnosis, prognosis, functional abilities, and formulating clinical intervention for both children and adults with neurodevelopmental disorders. Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders is an essential reference source that discusses and disseminates contributions covering recent trends in diagnosis, assessment, and intervention techniques. Featuring research on topics such as clinical linguistics, neural connectivity, and animal-assisted therapy, this book is ideally designed for speech pathologists, social workers, occupational therapists, psychologists, psychiatrists, neurologists, pediatricians, researchers, clinicians, and academicians seeking coverage on neural and developmental disorder identification and strategies for clinician support and therapies.


Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update by Roberto Canitano,Yuri Bozzi

Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update
  • Title : Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update
  • Author : Roberto Canitano,Yuri Bozzi
  • Publisher : Frontiers Media SA
  • ISBN Code : 2889452662
  • Pages : N.A
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

This Research Topic has the aim to fill the gap of the many unresolved scientific issues on Autism Spectrum Disorders (ASD) that are still in need of investigation, Targeted treatments based on the understanding of the underlying pathogenic mechanisms of disease are still lacking. Further research is awaited and should be obtained through a significant effort on experimental treatment trials and neuroscience research. This Topic is divided in two main sections, one covering clinical issues and another on basic neurosciences of Autism Spectrum Disorders. A more detailed description of the contents of the articles is provided in the editorial at the beginning of the issue.


Neurodevelopmental Disorders by Bin Chen,Kenneth Y. Kwan

Neurodevelopmental Disorders
  • Title : Neurodevelopmental Disorders
  • Author : Bin Chen,Kenneth Y. Kwan
  • Publisher : Academic Press
  • ISBN Code : 0128144092
  • Pages : 426
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Covers disorders of the nervous system that arise through defects in neural development


The Oxford Handbook of Clinical Child and Adolescent Psychology by Thomas H. Ollendick,Susan W. White,Bradley A. White

The Oxford Handbook of Clinical Child and Adolescent Psychology
  • Title : The Oxford Handbook of Clinical Child and Adolescent Psychology
  • Author : Thomas H. Ollendick,Susan W. White,Bradley A. White
  • Publisher : Oxford Library of Psychology
  • ISBN Code : 0190634847
  • Pages : 816
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

At the founding in 1896 of the first psychological clinic dedicated to children and adolescents, the study of the psychological treatment of young people lagged behind that of adults, and the basic psychopathology underlying mental disorders in this population was largely ignored. Since those early days, the field has evolved steadily and, in recent years, exponentially. The Oxford Handbook of Clinical Child and Adolescent Psychology is a state-of-the-science volume providing comprehensive coverage of the psychological problems and disorders of childhood. International in scope and penned by the discipline's most eminent scientists and practitioners, the handbook begins with a section on conceptual and empirical issues, followed by exceptional content on specific psychiatric disorders such as intellectual disability, externalizing and internalizing disorders, communication disorders, schizophrenia and bipolar disorder, personality disorders, and many more. The third section offers chapters on special problems in childhood and adolescence, including divorce, the incarceration of parents, suicide and non-suicidal self-injury, bullying, and medical illness. A fourth section covers delivery of clinical services in diverse settings, such as schools and prisons, and the handbook concludes with several chapters on emerging trends and future directions for the field. Conceptually rich and evidence-based, this handbook is an essential resource for students, practitioners, and researchers, providing a cutting-edge compendium of the latest theoretical and empirical developments by leaders of the discipline.


The Neurobiology of Schizophrenia by Ted Abel

The Neurobiology of Schizophrenia
  • Title : The Neurobiology of Schizophrenia
  • Author : Ted Abel
  • Publisher : Academic Press
  • ISBN Code : 9780128018293
  • Pages : 468
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

"The Neurobiology of Schizophrenia "begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophreniaDiscusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levelsEdited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevanceElucidates connections between the various systems depicted, when possible


The Fragile X-Associated Tremor Ataxia Syndrome (FXTAS) by Flora Tassone,Elizabeth M. Berry-Kravis

The Fragile X-Associated Tremor Ataxia Syndrome (FXTAS)
  • Title : The Fragile X-Associated Tremor Ataxia Syndrome (FXTAS)
  • Author : Flora Tassone,Elizabeth M. Berry-Kravis
  • Publisher : Springer Science & Business Media
  • ISBN Code : 9781441958051
  • Pages : 188
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

In Fragile X-Associated Tremor Ataxia Syndrome (FXTAS), the editors present information on all aspects of FXTAS, including clinical features and current supportive management, radiological, psychological, and pathological findings, genotype-phenotype relationships, animal models and basic molecular mechanisms. Genetic counseling issues are also discussed. The book should serve as a resource for professionals in all fields regarding diagnosis, management, and counseling of patients with FXTAS and their families, as well as presenting the molecular basis for disease that may lead to the identification of new markers to predict disease risk and eventually lead to target treatments.


Adolescent Addiction by Cecilia A. Essau

Adolescent Addiction
  • Title : Adolescent Addiction
  • Author : Cecilia A. Essau
  • Publisher : Elsevier
  • ISBN Code : 9780080559797
  • Pages : 344
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Adolescent Addiction: Epidemiology, Assessment, and Treatment presents a comprehensive review of information on adolescent addiction, including prevalence and co-morbidity rates, risk factors to addiction, and prevention and treatment strategies. Unlike other books that may focus on one specific addiction, this book covers a wide range of addictions in adolescents, including alcohol, cannabis, tobacco, eating, gambling, internet and video games, and sex addiction. Organized into three sections, the book begins with the classification and assessment of adolescent addiction. Section two has one chapter each on the aforementioned addictions, discussing for each the definition, epidemiology, risk factors, co-morbidity, course and outcome, and prevention and intervention. Section three discusses the assessment and treatment of co-morbid conditions in greater detail as well as the social and political implications of adolescent addictions. Intended to be of practical use to clinicians treating adolescent addiction, the book contains a wealth of information that will be of use to the researcher as well. Contributors to the book represent the US, Canada, the UK, New Zealand, and Australia. About the Editor: Cecilia A. Essau is professor of developmental psychopathology at Roehampton University in London, UK. Specializing in child and adolescent psychopathology, she has been an author or editor of 12 previous books in child psychopathology and is author of over 100 research articles and book chapters in this area. Comprehensive with the state-of-the-art information on important and the most common adolescent addiction Easy to understand and organized chapters Written by international experts


Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders by Lindsay M. Oberman,Peter G. Enticott

Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders
  • Title : Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders
  • Author : Lindsay M. Oberman,Peter G. Enticott
  • Publisher : Academic Press
  • ISBN Code : 0128127783
  • Pages : 368
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders provides a comprehensive overview of neurotechnological devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents. Many neuropsychiatric disorders are covered such as Autism Spectrum Disorder, ADHD, Depression, Tourette’s Syndrome, and OCD. Different device-based treatments are discussed such as Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation, Deep Brain Stimulation, Chronotherapy, and Neurofeedback. Provides an overview of neuromodulatory devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents Gives evidence-based recommendations for non-drug interventions that may be effective for treatment options Discusses different neuromodulatory treatment options, including TMS, tDCS, DBS, chronotherapy and neurofeedback


ADHD by Jill M. Norvilitis

ADHD
  • Title : ADHD
  • Author : Jill M. Norvilitis
  • Publisher : BoD – Books on Demand
  • ISBN Code : 9535121669
  • Pages : 390
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

With many children and adults affected by Attention Deficit Hyperactivity Disorder, researchers strive to improve our understanding of the causes, consequences, and treatment of the disorder. This volume examines some of the broad arrays of research in the field of ADHD, from etiology to cutting-edge interventions. The 16 chapters explore topics ranging from comorbidity to advances in the search for biomarkers; to executive, cognitive, and social functioning; to the use of new and alternative therapies. Both the professional and the casual reader alike will find something of interest, whether learning about ADHD for the first time or looking for inspiration for new research questions or potential interventions.


Autism Spectrum Disorder by Michael Fitzgerald

Autism Spectrum Disorder
  • Title : Autism Spectrum Disorder
  • Author : Michael Fitzgerald
  • Publisher : BoD – Books on Demand
  • ISBN Code : 9535120379
  • Pages : 378
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

This book starts with a new sub category of Autism Criminal Autistic Psychopathy and school shootings. It focuses on a number of interventions, including speech and language pathology, speech and language assessment instruments, occupational therapy, improving functional language development in autism with natural gestures, communication boards etc as well as helping people with autism using the pictorial support, training of concepts of significant others, theory of mind, social concepts and a conceptual model for empowering families of children with autism cross culturally. It also examines the issue of hyperandrogenism and evidence-based treatments of autism. In terms of assessment, it focuses on psychological and biological assessment including neurotransmitters systems, structural and functional brain imaging, coping strategies of parents, examines the intertwining of language impairment, specific language impairment and ASD, as well as implicit and spontaneous Theory of Mind reading in ASD. In terms of aetiology, it focuses on genetic factors, epigenetics, synaptic vesicles, toxicity during neurodevelopment, immune system and sex differences. It also examines the link between social cognitive anatomical and neurophysiologic biomarkers and candidate genes. This book will be relevant to all mental health professionals because autism occurs in all the different areas of psychiatry and professionals who will find it helpful will be psychiatrists, psychologists, social workers, nurses, teachers and all those working with persons with Autism including parents who nowadays are interested in knowing more and more, at a detailed level about their children or adults with autism.


Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability by Carlo Sala,Chiara Verpelli

Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability
  • Title : Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability
  • Author : Carlo Sala,Chiara Verpelli
  • Publisher : Academic Press
  • ISBN Code : 9780128001097
  • Pages : 600
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Autism Spectrum Disorders are lifelong neurodevelopmental disorders with early clinical presentation that affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite its high prevalence and insidious nature, there remains to be an extensive resource that provides information about the background and state of current research in the autism field. The first edition of Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. This volume discusses these neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms. *Introduces the genetic and non-genetic causes of autism and associated intellectual disabilities *Describes the genes implicated in ASDs and their function *Considers major individual genetic causes of autism, Rett syndrome, Fragile X syndrome, and other autism spectrum disorders, as well as their classification as synaptopathies *Thorough discussion of the clinical aspects of multiple neurodevelopmental disorders and the experimental models that exist to study their pathophysiology in vitro and in vivo, including animal models and patient-derived stem cell culture


Neurobiology of Brain Disorders by Michael J. Zigmond,Joseph T. Coyle,Lewis P. Rowland

Neurobiology of Brain Disorders
  • Title : Neurobiology of Brain Disorders
  • Author : Michael J. Zigmond,Joseph T. Coyle,Lewis P. Rowland
  • Publisher : Elsevier
  • ISBN Code : 0123982804
  • Pages : 824
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material


Sleep and ADHD by Harriet Hiscock,Emma Sciberras

Sleep and ADHD
  • Title : Sleep and ADHD
  • Author : Harriet Hiscock,Emma Sciberras
  • Publisher : Academic Press
  • ISBN Code : 9780128141809
  • Pages : 375
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Sleep and ADHD begins with an overview of sleep (normal sleep, sleep cues, developmental phases, etc.) and continues with the epidemiology of ADHD and sleep problems, including medical issues (e.g. sleep apnea), parasomnias, behavioral insomnias (i.e. limit setting, sleep onset association disorders, circadian rhythm disorders and anxiety-related insomnia). It then covers the etiology of sleep problems, including the role of sleep hygiene and habits, the developing child, and the role of stimulants and medications used in the management of ADHD sleep problems. As the first book of its kind, users will find this reference an invaluable addition to the literature on ADHD. Covers both the pharmacological and non-pharmacological management of sleep problems Addresses sleep issues in younger children, but also addresses adolescents and adults Discusses the impact of sleep problems on the family as well as the child with ADHD Reviews the evidence around the neurobiology of sleep and systems regulating sleep in ADHD


Trauma, Autism, and Neurodevelopmental Disorders by Jason M. Fogler,Randall A. Phelps

Trauma, Autism, and Neurodevelopmental Disorders
  • Title : Trauma, Autism, and Neurodevelopmental Disorders
  • Author : Jason M. Fogler,Randall A. Phelps
  • Publisher : Springer
  • ISBN Code : 9783030005023
  • Pages : 296
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

This book examines the diagnostic overlap and frequent confusion between the newly named DSM-5 diagnostic categories of neurodevelopmental disorders (NDDs), which include autism spectrum disorder (ASD), and trauma and stressor related disorders (TSRDs). These conditions are similar in that a) children with developmental disorders are particularly vulnerable to traumatic events and b) all have pervasive effects on the brain and development. Chapters provide a wealth of effective clinical, family, and school-based interventions, developed from established studies and important new findings. In addition, chapters use illustrative case studies to survey assessment challenges in today’s healthcare climate and consider alternative routes for improving correct diagnoses, identifying appropriate interventions, and referring proper targeted, evidence-based treatment and services. The book concludes with the editors’ recommendations for needs-based service access, including a more widespread use and acceptance of the Research Domain Criteria (RDoC) and the International Classification of Functioning, Disability, and Health (ICF) framework. Topics featured in this book include: The neurobiological contributors to posttraumatic stress disorder (PTSD). Fetal alcohol spectrum disorders (FASDs) and its diagnosis in children with a history of trauma. Interventions for trauma and stressor-related disorders in preschool-aged children. Reactive attachment disorder (RAD) and autism spectrum disorder (ASD) diagnosis and care in a cultural context. Special population consideration in ASD identification and treatment. Challenges associated with the transition to adulthood. Trauma and neurodevelopmental disorders from a public health perspective. Trauma, Autism, and Neurodevelopmental Disorders is a must-have resource for researchers, clinicians and related professionals, and graduate students in developmental psychology, child and adolescent psychiatry, public health, social work, pediatrics, and special education.


Clinical Staging in Psychiatry by Patrick D. McGorry,Ian B. Hickie

Clinical Staging in Psychiatry
  • Title : Clinical Staging in Psychiatry
  • Author : Patrick D. McGorry,Ian B. Hickie
  • Publisher : Cambridge University Press
  • ISBN Code : 1108718841
  • Pages : 300
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Clinical staging is a solution to transform psychiatric diagnosis and improve mental health outcomes.


Genomics, Circuits, and Pathways in Clinical Neuropsychiatry by Thomas Lehner,Bruce L. Miller,Matthew W. State

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry
  • Title : Genomics, Circuits, and Pathways in Clinical Neuropsychiatry
  • Author : Thomas Lehner,Bruce L. Miller,Matthew W. State
  • Publisher : Academic Press
  • ISBN Code : 0128005300
  • Pages : 796
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics Identifies key concepts, methods, and findings Includes coverage of multiple disorders from autism to schizophrenia Reviews specific genes associated with disorders Discusses the genetic architecture of these syndromes Explains how recent findings are influencing the understanding of biology Clarifies the promise of these findings for future treatment


Handbook of Developmental Neurotoxicology by William Slikker, Jr.,Louis W. Chang

Handbook of Developmental Neurotoxicology
  • Title : Handbook of Developmental Neurotoxicology
  • Author : William Slikker, Jr.,Louis W. Chang
  • Publisher : Elsevier
  • ISBN Code : 9780080533438
  • Pages : 748
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

The Handbook of Developmental Neurotoxicology provides a comprehensive account of the impacts, mechanisms, and clinical relevances of chemicals on the development of the nervous system. The book is written by internationally recognized experts on developmental neurotoxicology, covering subjects from basic neuro-development to toxic syndromes induced by various chemicals. It is an important text for both students and professionals who are interested in developmental neurobiology and neurotoxicology. Written by internationally recognized experts on developmental neurotoxicology Includes extensive references Well illustrated with diagrams, charts and tables Provides coverage of basic neurobiology as well as neurotoxicology


Neurological Disorders by World Health Organization

Neurological Disorders
  • Title : Neurological Disorders
  • Author : World Health Organization
  • Publisher : World Health Organization
  • ISBN Code : 9241563362
  • Pages : 218
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Although there are several gaps in understanding the many issues related to neurological disorders, we know enough to be able to shape effective policy responses to some of the most common. This book describes and discusses the increasing public health impact of common neurological disorders such as dementia, epilepsy, headache disorders, multiple sclerosis, neuroinfections, neurological disorders associated with malnutrition, pain associated with neurological disorders, Parkinson's disease, stroke and traumatic brain injuries. It provides information and advice on public health interventions that may reduce their occurrence and consequences, and offers health professionals and planners the opportunity to assess the burden caused by these disorders. The clear message that emerges is that unless immediate action is taken globally, the neurological burden is likely to become an increasingly serious and unmanageable.


Neuropsychiatric Disorders and Epigenetics by Dag Yasui,Dennis R. Grayson,Jacob Peedicayil

Neuropsychiatric Disorders and Epigenetics
  • Title : Neuropsychiatric Disorders and Epigenetics
  • Author : Dag Yasui,Dennis R. Grayson,Jacob Peedicayil
  • Publisher : Academic Press
  • ISBN Code : 9780128002261
  • Pages : 400
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

"Neurobehavioral Disorders and Epigenetics" is a comprehensive reference for the epigenetic basis of most common neurobehavioral disorders. The volume is organized into 22 chapters representing individual neurological disorders, from Addiction to Stress. The epigenetic aspects of each disorder are addressed by at least two scientists with expertise in that research area. Particular emphasis is placed by each contributing author on potential epigenetic interventions. In an effort to cover a broad range of epigenetic mechanisms including DNA modification, histone post-translational modification, chromatin organization and non-coding RNA, author contributions were selected accordingly. In addition the effects of environmental stimuli on epigenetic states is addressed in some chapters based on relevance to disease induction. Recent discoveries in epigenetic research enabled by advances in genomic technologies, have positioned the field for broad translation to therapeutic interventions for previously unmanageable disorders. Clearly neurobehavioral disorders represent a prime target of epigenetic interventions as they are highly debilitating, often chronic diseases with high costs to society. Thus, these collected works will define epigenetics as a key player in neurobehavioral disorders, highlight the full spectrum of epigenetic mechanisms underlying such disorders and introduce the vast range of epigenetic therapies under development. Relates the effects of environmental stimuli on epigenetic states to neurological disease inductionAnalysis of the epigenetic basis for common neuropsychiatric disorders and how it guides treatment, providing insight and perspective to both clinicians and basic scientistsExtensive use of diagrams, illustrations and tables, and graphical abstracts for each subsection permits rapid review


Neurodevelopmental Disorders by Emanuel DiCicco-Bloom,James H. Millonig

Neurodevelopmental Disorders
  • Title : Neurodevelopmental Disorders
  • Author : Emanuel DiCicco-Bloom,James H. Millonig
  • Publisher : Springer Nature
  • ISBN Code : 3030454932
  • Pages : 305
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

This book contains a compendium of induced pluripotent stem cells (iPSCs) articles and reviews concerning state of the art technologies and how they are being applied to human neurodevelopmental disorders. With the establishment of effective technologies to produce iPSCs and their derivatives, like neural precursors, neurons, and glia, researchers have new platforms to study neurodevelopmental disorders. iPSC technology enables researchers to study how human neurons develop in individuals with neurodevelopmental disorders, providing an unparalleled opportunity to investigate their etiology. In turn, researchers have now begun to understand the underlying molecular and cellular pathways that contribute to human diseases. iPSCs technologies also provide an emerging tool for future translational studies and disease classification. The chapters will emphasize how among the diverse idiopathic and genetic disorders, there are common clinical as well as cellular and molecular phenotypes.


Clinical Handbook of Schizophrenia by Kim Tornvall Mueser,Dilip V. Jeste

Clinical Handbook of Schizophrenia
  • Title : Clinical Handbook of Schizophrenia
  • Author : Kim Tornvall Mueser,Dilip V. Jeste
  • Publisher : Guilford Press
  • ISBN Code : 1609182375
  • Pages : 650
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Reviewing the breadth of current knowledge on schizophrenia, this handbook provides clear, practical guidelines for effective assessment and treatment in diverse contexts. Leading authorities have contributed 61 concise chapters on all aspects of the disorder and its clinical management. In lieu of exhaustive literature reviews, each chapter summarizes the state of the science; highlights key points the busy practitioner needs to know; and lists recommended resources, including seminal research studies, invaluable clinical tools, and more. Comprehensive, authoritative, and timely, the volume will enable professionals in any setting to better understand and help their patients or clients with severe mental illness.


The Neuroscience of Hallucinations by Renaud Jardri,Arnaud Cachia,Pierre Thomas,Delphine Pins

The Neuroscience of Hallucinations
  • Title : The Neuroscience of Hallucinations
  • Author : Renaud Jardri,Arnaud Cachia,Pierre Thomas,Delphine Pins
  • Publisher : Springer Science & Business Media
  • ISBN Code : 1461441218
  • Pages : 566
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Hallucinatory phenomena have held the fascination of science since the dawn of medicine, and the popular imagination from the beginning of recorded history. Their study has become a critical aspect of our knowledge of the brain, making significant strides in recent years with advances in neuroimaging, and has established common ground among what normally are regarded as disparate fields. The Neuroscience of Hallucinations synthesizes the most up-to-date findings on these intriguing auditory, visual, olfactory, gustatory, and somatosensory experiences, from their molecular origins to their cognitive expression. In recognition of the wide audience for this information among the neuroscientific, medical, and psychology communities, its editors bring a mature evidence base to highly subjective experience. This knowledge is presented in comprehensive detail as leading researchers across the disciplines ground readers in the basics, offer current cognitive, neurobiological, and computational models of hallucinations, analyze the latest neuroimaging technologies, and discuss emerging interventions, including neuromodulation therapies, new antipsychotic drugs, and integrative programs. Among the topics covered: Hallucinations in the healthy individual. A pathophysiology of transdiagnostic hallucinations including computational and connectivity modeling. Molecular mechanisms of hallucinogenic drugs. Structural and functional variations in the hallucinatory brain in schizophrenia. The neurodevelopment of hallucinations. Innovations in brain stimulation techniques and imaging-guided therapy. Psychiatrists, neurologists, neuropsychologists, cognitive neuroscientists, clinical psychologists, and pharmacologists will welcome The Neuroscience of Hallucinations as a vital guide to the current state and promising future of their shared field.


The Molecular Basis of Autism by S. Hossein Fatemi

The Molecular Basis of Autism
  • Title : The Molecular Basis of Autism
  • Author : S. Hossein Fatemi
  • Publisher : Springer
  • ISBN Code : 1493921908
  • Pages : 437
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

This book is a comprehensive overview of the clinical and scientific aspects of Autism from the leading experts in the field. The clinical section covers everything from epidemiological features to epigenetic regulation to behavioral therapies and much in between. The basic science section presents the latest knowledge on the underlying causes of the disorder including the role of various neurotransmitters, neurexins and neuroligins, reelin, and other proteins. Chapters also explore the cognition and motor control in autism and the connection between oxidative stress and mitochondrial dysfunction and autism. The thorough description of these underlying causes may help researchers and clinicians find more effective treatments and therapies for the 1 in 68 American children who have been diagnosed with Autism.


Behavioral Neurobiology of Bipolar Disorder and its Treatment by Husseini K. Manji,Carlos A. Zarate Jr.

Behavioral Neurobiology of Bipolar Disorder and its Treatment
  • Title : Behavioral Neurobiology of Bipolar Disorder and its Treatment
  • Author : Husseini K. Manji,Carlos A. Zarate Jr.
  • Publisher : Springer Science & Business Media
  • ISBN Code : 9783642157578
  • Pages : 347
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

This book offers the most up-to-date information about research surrounding the neurobiology of bipolar disorder as well as currently available and novel therapeutic options. The volume has assembled a widely respected group of preclinical and clinical researchers who bring their expertise to bear upon this illness by reviewing cutting-edge research and clinical evidence regarding the pathophysiology and treatment of bipolar disorder. Early chapters review the course and outcome and genetics of this highly heritable condition, including chapters on epigenetics and clinical endophenotypes. Several chapters offer a remarkably thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work and the development of animal models. Finally, the book covers treatment strategies for bipolar disorder, including both traditional and novel therapeutics, as well as non-pharmacological treatments. It offers both researchers and clinicians key insights into this devastating disorder.


Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease by Roger N. Rosenberg,Juan M. Pascual

Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease
  • Title : Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease
  • Author : Roger N. Rosenberg,Juan M. Pascual
  • Publisher : Academic Press
  • ISBN Code : 9780124105294
  • Pages : 1464
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

" ... With this new edition the three key markets, research scientists, clinicians, and genetic counselors will all continue to benefit from the content. The research community will find great value in the coverage of genomics, animal models, and diagnostic methods along with a a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations. And genetic counselors will find this a comprehensive tutorial reference on the latest advances in the science, with links to genetic testing for specific diseases.


The Neurobiology and Genetics of Gilles de la Tourette Syndrome: New Avenues Through Large-Scale Collaborative Projects by Peristera Paschou,Kirsten R. Müller-Vahl

The Neurobiology and Genetics of Gilles de la Tourette Syndrome: New Avenues Through Large-Scale Collaborative Projects
  • Title : The Neurobiology and Genetics of Gilles de la Tourette Syndrome: New Avenues Through Large-Scale Collaborative Projects
  • Author : Peristera Paschou,Kirsten R. Müller-Vahl
  • Publisher : Frontiers Media SA
  • ISBN Code : 2889453235
  • Pages : N.A
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as histamine and glutamate. For a very long time, efforts to elucidate the etiology and pathophysiology of TS have been fragmented and hampered by low statistical power. Finally, after more than two decades of active research aiming to identify the etiology and pathophysiology of TS, we are on the verge of a new era, promising exciting and rapid discoveries in the field. Investigators from around the world, representing multiple disciplines and scientific approaches, are joining their efforts in large-scale initiatives supported both by European Union and US National funding agencies, such as the European-funded EMTICS, TACTICS, and TSGeneSEE consortia, the Marie Curie Initial Training Network TS-EUROTRAIN and the European Society for the Study of TS joining forces with the NIH-funded TSAICG, GGRI, and Tic Genetics consortia. Importantly, all these initiatives are supported by TS patient support and advocacy groups. Multiple resources are being consolidated and coming together to serve the study of TS, including large well-characterized patient cohorts, and specialized epidemiological databases, such as the unique resource of the Netherlands Twin Register. This research topic showcases current large-scale collaborative efforts aiming to elucidate the genetic and neurobiological background of TS, through diverse approaches; from genomewide association studies aiming to identify common variants associated to the disorder to neuroimaging studies and animal models. Furthermore, current approaches on the clinical assessment and management of the disorder are presented. Propelled by the gradual availability of large scale TS cohorts, novel methodologies, and importantly, sheer enthusiasm by multiple researchers working together across different countries, the new era of the neurobiology of TS holds the promise to identify novel targets for improved therapies.


Child and Adolescent Mental Health by Martin Henrik Maurer

Child and Adolescent Mental Health
  • Title : Child and Adolescent Mental Health
  • Author : Martin Henrik Maurer
  • Publisher : BoD – Books on Demand
  • ISBN Code : 9535131893
  • Pages : 218
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

In the present volume, we collected state-of-the-art chapters on diagnosis, treatment, and social implications. The first section describes diagnostic processes. It describes a reevaluation of projective techniques, a new clinical tool in psychotraumatology, the foundations of the framing technique, and an overview on integrative approaches. The second section focuses on new developments in the field with special emphasis on culture-specific contexts. From parenting of adolescents in India to the influence of poverty on mental health issues in Mexico, as well as the use of marijuana and Internet addiction, some of the most important fields are highlighted. The third section concentrates on therapy. It shows how to react to bullying and reviews the use of antidepressants in children and adolescents.


Neurological, Psychiatric, and Developmental Disorders by Institute of Medicine,Board on Global Health,Committee on Nervous System Disorders in Developing Countries

Neurological, Psychiatric, and Developmental Disorders
  • Title : Neurological, Psychiatric, and Developmental Disorders
  • Author : Institute of Medicine,Board on Global Health,Committee on Nervous System Disorders in Developing Countries
  • Publisher : National Academies Press
  • ISBN Code : 9780309170932
  • Pages : 458
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Brain disordersâ€"neurological, psychiatric, and developmentalâ€"now affect at least 250 million people in the developing world, and this number is expected to rise as life expectancy increases. Yet public and private health systems in developing countries have paid relatively little attention to brain disorders. The negative attitudes, prejudice, and stigma that often surround many of these disorders have contributed to this neglect. Lacking proper diagnosis and treatment, millions of individual lives are lost to disability and death. Such conditions exact both personal and economic costs on families, communities, and nations. The report describes the causes and risk factors associated with brain disorders. It focuses on six representative brain disorders that are prevalent in developing countries: developmental disabilities, epilepsy, schizophrenia, bipolar disorder, depression, and stroke. The report makes detailed recommendations of ways to reduce the toll exacted by these six disorders. In broader strokes, the report also proposes six major strategies toward reducing the overall burden of brain disorders in the developing world.


Frontiers in Autism Research by Valerie W. Hu

Frontiers in Autism Research
  • Title : Frontiers in Autism Research
  • Author : Valerie W. Hu
  • Publisher : World Scientific Publishing Company Incorporated
  • ISBN Code : 9789814602150
  • Pages : 697
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

This unique book focuses on the emerging and expanding areas of research on autism spectrum disorders (ASD). These areas include investigations of genome-wide genetics and epigenetic contributions, metabolic and immune dysfunction, gene-environment interactions, as well as the role of alternative splicing, RNA editing, and noncoding RNAs in gene regulation. Advances in targeted or personalized therapies and alternative interventions, such as music and art therapy, are also presented. In addition, current research on issues involving adults with ASD, a population that has been sorely neglected in the field of autism, is discussed. Within each chapter, experts will review the current status of autism research in his/her field as well as provide a look at the direction where the field will (or should) be headed over the next five years and discuss the translational (practical) outcomes that are anticipated through this research. Some chapters are devoted to the development of molecular or genetic diagnostics for ASD, and novel therapeutic options that are emerging based upon new biological findings on specific genes, pathways, and metabolic functions disrupted in ASD. These unique features are designed to provide "food for thought" for future studies on autism. Hence, this book will be of value not only to established investigators and students conducting research on autism, but also to the general population especially families of individuals affected by ASDs.


Neural Circuit Development and Function in the Healthy and Diseased Brain by N.A

Neural Circuit Development and Function in the Healthy and Diseased Brain
  • Title : Neural Circuit Development and Function in the Healthy and Diseased Brain
  • Author : N.A
  • Publisher : Academic Press
  • ISBN Code : 0123973465
  • Pages : 848
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 3 offers 40 high level articles devoted mainly to anatomical and functional development of neural circuits and neural systems, as well as those that address neurodevelopmental disorders in humans and experimental organisms. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 3 sections include coverage of: mechanisms that control the assembly of neural circuits in specific regions of the nervous system, multiple aspects of cognitive development, and disorders of the nervous system arising through defects in neural development


Educating Children with Autism by National Research Council,Division of Behavioral and Social Sciences and Education,Board on Children, Youth and Families,Board on Behavioral, Cognitive, and Sensory Sciences,Committee on Educational Interventions for Children with Autism

Educating Children with Autism
  • Title : Educating Children with Autism
  • Author : National Research Council,Division of Behavioral and Social Sciences and Education,Board on Children, Youth and Families,Board on Behavioral, Cognitive, and Sensory Sciences,Committee on Educational Interventions for Children with Autism
  • Publisher : National Academies Press
  • ISBN Code : 0309210011
  • Pages : 324
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Autism is a word most of us are familiar with. But do we really know what it means? Children with autism are challenged by the most essential human behaviors. They have difficulty interacting with other people-often failing to see people as people rather than simply objects in their environment. They cannot easily communicate ideas and feelings, have great trouble imagining what others think or feel, and in some cases spend their lives speechless. They frequently find it hard to make friends or even bond with family members. Their behavior can seem bizarre. Education is the primary form of treatment for this mysterious condition. This means that we place important responsibilities on schools, teachers and children's parents, as well as the other professionals who work with children with autism. With the passage of the Individuals with Disabilities Education Act of 1975, we accepted responsibility for educating children who face special challenges like autism. While we have since amassed a substantial body of research, researchers have not adequately communicated with one another, and their findings have not been integrated into a proven curriculum. Educating Children with Autism outlines an interdisciplinary approach to education for children with autism. The committee explores what makes education effective for the child with autism and identifies specific characteristics of programs that work. Recommendations are offered for choosing educational content and strategies, introducing interaction with other children, and other key areas. This book examines some fundamental issues, including: How children's specific diagnoses should affect educational assessment and planning How we can support the families of children with autism Features of effective instructional and comprehensive programs and strategies How we can better prepare teachers, school staffs, professionals, and parents to educate children with autism What policies at the federal, state, and local levels will best ensure appropriate education, examining strategies and resources needed to address the rights of children with autism to appropriate education. Children with autism present educators with one of their most difficult challenges. Through a comprehensive examination of the scientific knowledge underlying educational practices, programs, and strategies, Educating Children with Autism presents valuable information for parents, administrators, advocates, researchers, and policy makers.


Autism 360° by Undurti N. Das,Neophytos Papaneophytou,Tatyana El-Kour

Autism 360°
  • Title : Autism 360°
  • Author : Undurti N. Das,Neophytos Papaneophytou,Tatyana El-Kour
  • Publisher : Academic Press
  • ISBN Code : 0128184671
  • Pages : 554
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Autism 360 uses a hybrid and transdisciplinary methodology to identify mechanisms on how autism is prevented, diagnosed, treated and managed within personal and social constructs around the world. Adopting a lifespan approach, the book discusses lifestyle challenges and emphasizes issues relating to neurodiversity, individuality, best practices, and support of both people on the spectrum and their families. This book will help change population and individual attitudes and behaviors regarding autism. Its ultimate goal is to empower readers to become both agents of change and an integral part of the solution. Covers topics from the prevention and treatment of autism and how to live with it Adopts an integrated methods approach Features field experiences Provides valuable syntheses of scattered material Compares cross-cultural learnings Discusses the education and employment of those with autism


Neuropsychopharmacology by Kenneth L. Davis,American College of Neuropsychopharmacology

Neuropsychopharmacology
  • Title : Neuropsychopharmacology
  • Author : Kenneth L. Davis,American College of Neuropsychopharmacology
  • Publisher : Lippincott Williams & Wilkins
  • ISBN Code : 9780781728379
  • Pages : 2010
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Thoroughly updated and completely reorganized for a sharper clinical focus, the Fifth Edition of this world-renowned classic synthesizes the latest advances in basic neurobiology, biological psychiatry, and clinical neuropsychopharmacology. The book establishes a critical bridge connecting new discoveries in molecular and cellular biology, genetics, and neuroimaging with the etiology, diagnosis, and treatment of all neuropsychiatric disorders. Nine sections focus on specific groups of disorders, covering clinical course, genetics, neurobiology, neuroimaging, and current and emerging therapeutics. Four sections cover neurotransmitter and signal transduction, emerging methods in molecular biology and genetics, emerging imaging technologies and their psychiatric applications, and drug discovery and evaluation. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC


Epigenetic Regulation in the Nervous System by J. David Sweatt,Michael J. Meaney,Eric J. Nestler,Schahram Akbarian

Epigenetic Regulation in the Nervous System
  • Title : Epigenetic Regulation in the Nervous System
  • Author : J. David Sweatt,Michael J. Meaney,Eric J. Nestler,Schahram Akbarian
  • Publisher : Academic Press
  • ISBN Code : 0123944058
  • Pages : 374
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system. Behavioral epigenetics is the study of how environmental factors alter behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resilience to adverse behavioral outcomes. By understanding the molecular mechanisms involved in epigenetic modulation, researchers may be able to develop targeted therapies for those individuals in whom it malfunctions. Edited by the most highly regarded leaders in the field, this book offers a comprehensive review of behavioral epigenetics and a balanced treatment of the strengths and weaknesses in experimentation in this area. Covering background material as well as topics of current interest, it serves both as a cutting-edge resource and a foundational reference. The book will benefit neuroscience researchers and graduate students with an interest in the links between gene regulation and behavior, as will clinicians dealing with disorders such as addiction, depression, and schizophrenia. BMA Medical Book Awards 2014 - Highly Commended, Neurology, British Medical Association BMA Medical Book Awards 2014 - First Prize, Neurology, British Medical Association 2013 PROSE Award winner for Best in Reference Works and Best Single Volume Reference in Science from the Association of American Publishers Presents a unified view of epigenetic mechanisms from behavior to genes and everything in between Discusses clinically relevant disorders in the context of epigenetics research, making the volume appealing to clinicians as well as basic scientists Provides numerous practical examples for the new investigator to facilitate implementation of research in neuroepigenetics


Neurodevelopmental Disorders by Randi Jenssen Hagerman

Neurodevelopmental Disorders
  • Title : Neurodevelopmental Disorders
  • Author : Randi Jenssen Hagerman
  • Publisher : Oxford University Press
  • ISBN Code : 0198028695
  • Pages : 224
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Neurodevelopmental Disorders: Diagnosis and Treatment summarizes a vast body of literature concerning diagnosis and treatment for a variety of neurodevelopmental disorders, including both common and rare conditions. Throughout the book, Dr. Hagerman synthesizes treatment information for many disciplines that work together to provide multi-modality intervention. Psychopharmacological information and recommendations as well as the latest knowledge regarding genetic and diagnostic aspects of each disorder are explained in detail. And all chapters have one or more case studies to model the treatment recommendations, which are enhanced by extensive appendices reviewing educational programs, computer software, and supplementary reading. In addition, a detailed resource list of organizations, educational materials, and internet connections accompanies each chapter. This book not only integrates but also advances our knowledge of treatment, which is of prime importance for clinicians, therapists, educators, and parents.


The Neuroscience of Cocaine by Victor R. Preedy

The Neuroscience of Cocaine
  • Title : The Neuroscience of Cocaine
  • Author : Victor R. Preedy
  • Publisher : Academic Press
  • ISBN Code : 012803792X
  • Pages : 774
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

The Neuroscience of Cocaine: Mechanisms and Treatment explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms. Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine’s neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. Written by worldwide experts in cocaine addiction, this book assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse. Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Illustrated in full color Provides unique full coverage of all aspects of cocaine and its related pathology Provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms


Jasper's Basic Mechanisms of the Epilepsies by Jeffrey Noebels,Massimo Avoli,Michael Rogawski,Richard Olsen,Antonio Delgado-Escueta

Jasper's Basic Mechanisms of the Epilepsies
  • Title : Jasper's Basic Mechanisms of the Epilepsies
  • Author : Jeffrey Noebels,Massimo Avoli,Michael Rogawski,Richard Olsen,Antonio Delgado-Escueta
  • Publisher : Oxford University Press
  • ISBN Code : 0199842590
  • Pages : 1264
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a "better understanding of the epilepsies and seek more rational methods of their prevention and treatment." Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these goals in mind -- assessing where epilepsy research has been, what it has accomplished, and where it should go. In 1999, the third volume of BME was named in honor of H.H. Jasper. In line with the enormous expansion in the understanding of basic epilepsy mechanisms over the past four decades, this fourth edition of Jasper's BME is the most ambitious yet. In 90 chapters, the book considers the role of interactions between neurons, synapses, and glia in the initiation, spread and arrest of seizures. It examines mechanisms of excitability, synchronization, seizure susceptibility, and ultimately epileptogenesis. It provides a framework for expanding the epilepsy genome and understanding the complex heredity responsible for common epilepsies as it explores disease mechanisms of ion channelopathies and developmental epilepsy genes. It considers the mechanisms of conditions of epilepsy comorbidities. And, for the first time, this 4th edition describes the current efforts to translate the discoveries in epilepsy disease mechanisms into new therapeutic strategies. This book, considered the 'bible' of basic epilepsy research, is essential for the student, the clinician scientist and all research scientists who conduct laboratory-based experimental epilepsy research using cellular, brain slice and animal models, as well as for those interested in related disciplines of neuronal oscillations, network plasticity, and signaling in brain strucutres that include the cortex, hippocampus, and thalamus. In keeping with the 1969 goals, the book is now of practical importance to the clinical neurologist and epileptologist as the progress of research in molecular genetics and modern efforts to design antiepileptic drugs, cures and repairs in the epilepsies converge and impact clinical care.


Perinatal Programming of Neurodevelopment by Marta C. Antonelli

Perinatal Programming of Neurodevelopment
  • Title : Perinatal Programming of Neurodevelopment
  • Author : Marta C. Antonelli
  • Publisher : Springer
  • ISBN Code : 1493913727
  • Pages : 477
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

The development of the brain and nervous system is shaped not just by a genetic program, but also by the effects of multiple environmental stimuli. There are currently no book-length treatments of perinatal neurodevelopment. The proposed book seeks to fill this gap by presenting a collection of chapters from leading experts in the field. It is intended to be comprehensive and will cover all aspects of neurodevelopmental programming in lab animals and in human subjects. The third section of the book will look at ways of translating insights we have garnered from animal studies to human and clinical studies. The primary audience for this work is basic researchers interested in the effects of perinatal imprinting on the development of the nervous system and associated diseases.


Neuroscience of Alcohol by Victor R. Preedy

Neuroscience of Alcohol
  • Title : Neuroscience of Alcohol
  • Author : Victor R. Preedy
  • Publisher : Academic Press
  • ISBN Code : 0128131268
  • Pages : 736
  • Format : Pdf - ePub
  • Language : English
  • GET EBOOK

Summary:

Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world’s most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of alcohol use, along with its effects on neurobiological function Discusses alcohol use as a component of dual-use and poly addictions Outlines numerous screening and treatment strategies for alcohol misuse Covers both the physical and psychological effects of alcohol use and withdrawals to provide a fully-formed view of alcohol dependency and its effects